tDCS-induced enhancement of cognitive flexibility in autism: role of frontal lobe and associated neural circuits
Our results indicate that tDCS ameliorates ASD-like phenotypes in VPA rats, potentially through microglial suppression and PFC network synchronization. These findings support neuromodulation as a promising therapeutic approach for ASD-related cognitive dysfunction.
Authors
- Chenyi Xia (ORCID: https://orcid.org/0009-0001-2027-766X)
- Xianwen Dong (ORCID: https://orcid.org/0000-0002-8977-3485)
- Youcai Tang (ORCID: https://orcid.org/0000-0003-2087-6029)
- Wenjing Hu (ORCID: https://orcid.org/0000-0003-4375-1341)
- Anqin Dong
- Zihua Zhou (ORCID: https://orcid.org/0000-0003-3513-5020)
- Yanan Han (ORCID: https://orcid.org/0000-0002-3464-2656)
- Dongdong Cheng (ORCID: https://orcid.org/0000-0003-2939-1415)
- Liguo Li (ORCID: https://orcid.org/0000-0002-9945-5771)
- Pengyuan Zheng (ORCID: https://orcid.org/0000-0003-1647-0253)
- Zhe Zhang (ORCID: https://orcid.org/0000-0002-0899-8077)
- Shuo Zhang (ORCID: https://orcid.org/0000-0002-7696-8312)
- Hongyan Xu (ORCID: https://orcid.org/0000-0002-4916-2567)
- Chengming Xu (ORCID: https://orcid.org/0000-0003-3891-2227)
- Xinxin Cui (ORCID: https://orcid.org/0000-0002-4780-0027)
- Tingli He
Institutions
- Henan Academy of Sciences (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Fifth Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Frontiers in Behavioral Neuroscience
- Published
- 2025-08-12
- DOI
- https://doi.org/10.3389/fnbeh.2025.1631236
- Citations
- 2
- Primary Topic
- Autism Spectrum Disorder Research
- Type
- article
- Field-Weighted Citation Impact
- 2.86