Mitochondrial targeting ratiometric theranostic probe activated by hydrogen peroxide toward tracking pH variations in therapeutic processes
This study not only provides a new strategy for the design of activatable theranostic probe with organelle-targeting capabilities, but also establishes a novel method for monitoring dynamic cellular state changes during tumor treatment. The proposed approach shows potential to cancer diagnosis and treatment by enabling simultaneous imaging and therapeutic monitoring.
Authors
- Jing He (ORCID: https://orcid.org/0000-0002-7249-4746)
- Qiong Jia (ORCID: https://orcid.org/0000-0002-3799-0576)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-0704-7421)
- Huifeng Zhang (ORCID: https://orcid.org/0000-0002-1329-7240)
Institutions
- Jilin University (CN)
- Jilin Jianzhu University (CN)
- Jilin Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Analytica Chimica Acta
- Published
- 2025-08-11
- DOI
- https://doi.org/10.1016/j.aca.2025.344532
- Citations
- 2
- Primary Topic
- Molecular Sensors and Ion Detection
- Type
- article
- Field-Weighted Citation Impact
- 1.51
Funders
- State Key Laboratory of Supramolecular Structure and Materials