Analysis of Blood Components and Target Prediction for the Combined Use of Dendrobium officinale Compound and Western Medicine in Antihypertensive Therapy Based on Network Pharmacology and Molecular Docking
The combination of DOC with two Western medications has been shown to significantly enhance antihypertensive effects in SHRs. Furthermore, five major monomers present in the serum of experimental rats post-treatment exhibit notable antihypertensive properties.
Authors
- Renzhao Wu
- Xiyu Mei (ORCID: https://orcid.org/0000-0003-2206-7647)
- Jie Wang (ORCID: https://orcid.org/0000-0003-2227-1971)
- Yue Wu (ORCID: https://orcid.org/0000-0003-4628-7628)
- Zhansheng Guo (ORCID: https://orcid.org/0000-0001-5917-9517)
- Xiaomin Xue
- Lisha Zhao (ORCID: https://orcid.org/0000-0001-6941-5253)
- Huifang Zhou
- Tong Cheng
- CongLing Xi (ORCID: https://orcid.org/0000-0002-8257-8943)
Institutions
- Zhejiang Chinese Medical University (CN)
- Zhe jiang Research Institute of Traditional Chinese Medicine (China) (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/dddt.s522471
- Citations
- 1
- Primary Topic
- Biological and pharmacological studies of plants
- Type
- article
- Field-Weighted Citation Impact
- 1.39