Highlights from ESHRE 2025: Advances in Endometrial Preparation Strategies for Frozen Embryo Transfer

Frozen embryo transfer (FET) protocols play a pivotal role in assisted reproduction, with ongoing research focused on optimising outcomes through precise hormonal management and endometrial preparation.Progesterone monitoring during the luteal phase remains a critical yet debated factor influencing implantation success and pregnancy maintenance.In parallel, novel adjunct therapies, including intrauterine platelet-rich plasma (PRP) infusion, are under investigation for their potential to enhance endometrial receptivity, especially in patients with recurrent implantation failure (RIF).These areas of study highlight the evolving complexity of FET management and the ongoing pursuit of personalised treatment strategies to improve reproductive outcomes.