Alectinib Efficacy Post-Brigatinib Against Advanced ALK+ Non-Small Cell Lung Cancer (BrigALK2-GFPC 02-2019 Study)
According to the results of this retrospective real-world study, alectinib post-brigatinib showed limited overall activity but remains an option for patients with advanced <i>ALK</i>+ NSCLCs, especially when brigatinib was discontinued because of toxicity.
Authors
- H. Doubre
- R. Descourt (ORCID: https://orcid.org/0000-0003-2385-9507)
- C. Chouaïd (ORCID: https://orcid.org/0000-0002-4290-5524)
- B. Mennecier (ORCID: https://orcid.org/0000-0002-2321-4269)
- M. Pérol
- M. Duruisseaux (ORCID: https://orcid.org/0000-0003-1495-0966)
- Olivier Bylicki (ORCID: https://orcid.org/0000-0001-8683-0969)
- Laurent Greillier (ORCID: https://orcid.org/0000-0002-5807-9503)
- Florian Guisier (ORCID: https://orcid.org/0000-0002-8166-7303)
- Stéphane Culine (ORCID: https://orcid.org/0000-0003-1470-2698)
- Jacques Cadranel (ORCID: https://orcid.org/0000-0003-2446-2923)
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Aix-Marseille Université (FR)
- Sorbonne Université (FR)
- Assistance Publique Hôpitaux de Marseille (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre Hospitalier Régional et Universitaire de Nancy (FR)
- Centre Léon Bérard (FR)
- Hôpital Nord (FR)
- Centre de Recherche en Cancérologie de Lyon (FR)
- Centre Hospitalier Régional Universitaire de Brest (FR)
- Hôpital Louis Pradel (FR)
- Hôpital d'Instruction des Armées Sainte-Anne (FR)
- Hôpital Saint-Louis (FR)
- Centre Hospitalier Universitaire de Rouen (FR)
- Hôpital Foch (FR)
- Hôpital Maison Blanche (FR)
- Hôpital Tenon (FR)
- Université de Rouen Normandie (FR)
Publication Details
- Journal
- Lung Cancer Targets and Therapy
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/lctt.s522038
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 0.00