Bringing credibility to observational research in critical care: the case of target trial emulation designs

INTRODUCTION Historically, relying on observational data to evaluate causal effects has been considered a sin, with journals often advising authors to remove causal language from their results, whereas randomized clinical trials remain the gold standard for assessing the comparative effectiveness and safety of treatments.() However, clinical trials are often impractical, unethical, or untimely.() In addition, […]

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Publication Details

Journal
Critical Care Science
Published
2025-01-01
DOI
https://doi.org/10.62675/2965-2774.20250142
Primary Topic
Meta-analysis and systematic reviews
Type
article
Field-Weighted Citation Impact
0.00
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article

Bringing credibility to observational research in critical care: the case of target trial emulation designs

Sérgio Renato da Rosa Decker, Ary Serpa Neto
Critical Care Science
Meta-analysis and systematic reviews
article

Bringing credibility to observational research in critical care: the case of target trial emulation designs

Sérgio Renato da Rosa Decker, Ary Serpa Neto
article en

Abstract

INTRODUCTION Historically, relying on observational data to evaluate causal effects has been considered a sin, with journals often advising authors to remove causal language from their results, whereas randomized clinical trials remain the gold standard for assessing the comparative effectiveness and safety of treatments.() However, clinical trials are often impractical, unethical, or untimely.() In addition, […]

Critical Care ScienceVol. 37
Beth Israel Deaconess Medical Center (US), Hospital Israelita Albert Einstein (BR), Austin Hospital (AU), Hospital Moinhos de Vento (BR), Australian and New Zealand Intensive Care Society (AU), Deaconess Hospital (US)
Openalex Percentile: Top 80%
Meta-analysis and systematic reviews
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