Immunohistochemical Expression of SGLT2 in Pancreatic Ductal Adenocarcinoma

SGLT2 immunoexpression is significantly associated with the histological grade and tumor stage of PDAC. Hence, we suggest that SGLT2 inhibition can be a potential therapeutic strategy in moderate to advanced PDAC.

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Publication Details

Journal
Cureus
Published
2025-08-12
DOI
https://doi.org/10.7759/cureus.89878
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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0.00
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article

Immunohistochemical Expression of SGLT2 in Pancreatic Ductal Adenocarcinoma

Shristi Butta, Manoj Gupta
Cureus
Pancreatic and Hepatic Oncology Research
article

Immunohistochemical Expression of SGLT2 in Pancreatic Ductal Adenocarcinoma

Shristi Butta, Manoj Gupta
article en

Abstract

SGLT2 immunoexpression is significantly associated with the histological grade and tumor stage of PDAC. Hence, we suggest that SGLT2 inhibition can be a potential therapeutic strategy in moderate to advanced PDAC.

CureusVol. 17(8)
Institute of Post Graduate Medical Education and Research (IN), Hospital for Tropical Diseases (VN)
Zero hunger
Openalex Percentile: Top 70%
Pancreatic and Hepatic Oncology Research
DOIOpen Access PDFOpenAlex
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Immunohistochemical Expression of SGLT2 in Pancreatic Ductal Adenocarcinoma — Shristi Butta, Manoj Gupta · Cureus (2025) | TGRS Research Map | TGRS