Phyllodes Tumors of the Breast: About 34 Cases

Phyllodes tumors of the breast are rare fibroepithelial tumors. They are the subject of Controversy, particularly concerning terminology, histological classification and Treatment. The aim of this study is to highlight the epidemiological, clinical, paraclinical, therapeutic and prognostic features of these tumors. Patients and methods: This was a retrospective study of cases of phyllodes tumours Collected in the gynaecological-mammary surgery department of CHU Ibn Rochd, Casablanca, over a 6-year period. Results: Thirty-four patients were included in our study. The mean age was 30.2 years. A history of fibroadenoma was found in 20.58%. The mean tumor size was 7.3 cm. Diagnosis was based on breast ultrasound, with or without mammography depending on the patient’s age, and micro biopsy. Treatment consisted of lumpectomy in 76.47% of Cases. Grade III was found in 14.7% of cases. Eight patients had non-healthy resection Margins, 6 of whom underwent revision surgery. After 3 years and 3 months, there were Two cases of metastatic recurrence. Discussion: Phyllodes tumor of the breast is a rare entity. In our series, one of the Particularities is that it affects younger women in comparison with the literature. In the Majority of cases, it is benign, but histological examination must be meticulous in order to eliminate malignant forms. In benign forms, a wide lumpectomy with healthy Margins allows a favorable evolution with a very low risk of local recurrence. On the Other hand, in borderline and especially malignant forms, mastectomy seems to be Necessary in the majority of cases, along with adjuvant radiotherapy, to reduce the risk of local and metastatic recurrence. Conclusion: The frequency of benign forms should not blind us to the risk of malignant or even metastatic recurrence. This underlines the importance of correct initial Management.

Publication Details

Journal
Journal of Case Reports and Medical History
Published
2025-08-11
DOI
https://doi.org/10.54289/jcrmh2500143
Primary Topic
Breast Lesions and Carcinomas
Type
article
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article

Phyllodes Tumors of the Breast: About 34 Cases

Journal of Case Reports and Medical History
Breast Lesions and Carcinomas
article

Phyllodes Tumors of the Breast: About 34 Cases

article en

Abstract

Phyllodes tumors of the breast are rare fibroepithelial tumors. They are the subject of Controversy, particularly concerning terminology, histological classification and Treatment. The aim of this study is to highlight the epidemiological, clinical, paraclinical, therapeutic and prognostic features of these tumors. Patients and methods: This was a retrospective study of cases of phyllodes tumours Collected in the gynaecological-mammary surgery department of CHU Ibn Rochd, Casablanca, over a 6-year period. Results: Thirty-four patients were included in our study. The mean age was 30.2 years. A history of fibroadenoma was found in 20.58%. The mean tumor size was 7.3 cm. Diagnosis was based on breast ultrasound, with or without mammography depending on the patient’s age, and micro biopsy. Treatment consisted of lumpectomy in 76.47% of Cases. Grade III was found in 14.7% of cases. Eight patients had non-healthy resection Margins, 6 of whom underwent revision surgery. After 3 years and 3 months, there were Two cases of metastatic recurrence. Discussion: Phyllodes tumor of the breast is a rare entity. In our series, one of the Particularities is that it affects younger women in comparison with the literature. In the Majority of cases, it is benign, but histological examination must be meticulous in order to eliminate malignant forms. In benign forms, a wide lumpectomy with healthy Margins allows a favorable evolution with a very low risk of local recurrence. On the Other hand, in borderline and especially malignant forms, mastectomy seems to be Necessary in the majority of cases, along with adjuvant radiotherapy, to reduce the risk of local and metastatic recurrence. Conclusion: The frequency of benign forms should not blind us to the risk of malignant or even metastatic recurrence. This underlines the importance of correct initial Management.

Journal of Case Reports and Medical History
Openalex Percentile: Top 70%
Breast Lesions and Carcinomas
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