CHOROBA PARKINSONA W PODEJŚCIU METABOLOMICZNYM: OD ZABURZEŃ METABOLIZMU DO WCZESNEJ DIAGNOSTYKI

Parkinson’s disease is the second most common neurodegenerative disorder, characterized by the progressive loss of dopaminergic neurons and the emergence of both motor and non-motor symptoms. Despite the focus of current research, diagnosis remains a challenge, mainly due to the lack of specific biological markers. Metabolomics is a modern approach that enables the analysis of lowmolecular-weight chemical compounds (metabolites) in the body, offering new perspectives for understanding the pathophysiology of the disease and developing cutting-edge, effective diagnostic tools. This article discusses the application of the metabolomic approach in Parkinson’s disease. It also presents the potential of metabolomics and highlights its growing significance in early disease detection. This field may contribute to the development of faster, more accurate, and minimally invasive diagnostic methods, opening new possibilities in prevention and supporting clinical decision-making.