MORPHOLOGICAL VERIFICATION OF PULMONARY ASPERGILLOSIS

Aspergillosis of the lungs is an infectious disease caused by fungi of the genus Aspergillus , which can affect lung tissue, causing inflammation, necrosis and loss of function. This disease is becoming increasingly relevant due to the increasing number of patients with weakened immune systems, such as patients with chronic respiratory diseases (for example, COPD, asthma, etc.). The disease can occur in various forms, from acute and subacute to chronic and invasive, which makes diagnosis difficult and requires an individualized approach to treatment. Differential diagnosis of the pulmonary form of aspergillosis should be performed with tuberculosis, sarcoidosis, pneumonia (destructive forms), tumor processes and their metastases. The article presents a clinical case of disseminated pulmonary aspergillosis in a woman, in which it became difficult to clinically diagnose the pathological process without morphological verification. This clinical case shows that a pathologist should carry out a thorough morphological verification of the granulomatous process, taking into account clinical and laboratory data, radiation diagnostics and additional research methods, taking into account the peculiarities of the histological picture in each granulomatous disease. Differential diagnosis of granulomatous formations makes it possible to exclude other types of granulomatosis, in particular in tuberculosis, during histological examination of thoracobiopsy material. Timely morphological verification of the clinical diagnosis will make it possible to choose an adequate treatment strategy and assess the prognosis of the disease. Aspergillosis worsens the course of the underlying pathological process. Aspergillosis of the lungs is a serious threat to health, especially among patients with weakened immune systems. Early detection and accurate diagnosis of the disease play a key role in its successful treatment.