Xian Huang Fang Inhibits the PKCδ/MAPK Signaling Pathway to Attenuate Renal Tubular Epithelial Cell Senescence and Thereby Delay Renal Interstitial Fibrosis
XHF alleviates renal interstitial fibrosis by inhibiting the PKCδ/MAPK signaling pathway, thereby reducing the senescence of renal tubular epithelial cells.
Authors
- Kanjun Chen
- Xü Lin (ORCID: https://orcid.org/0000-0002-6382-7414)
- Tingting Li (ORCID: https://orcid.org/0000-0002-0628-5209)
- Xiaoxi Du (ORCID: https://orcid.org/0000-0002-1500-1247)
- Wang Yanru (ORCID: https://orcid.org/0009-0008-8306-9017)
- Minghai Shao (ORCID: https://orcid.org/0009-0002-6571-4082)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/dddt.s522318
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.43