Factors Associated with Exertional Desaturation in Patients with Chronic Obstructive Pulmonary Disease

The six minute walk test (6MWT) has a prognostic role in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to determine the factors associated with desaturation during the 6MWT in patients with COPD. This study utilized data from the prospective KOrea COPD Subgroup Study (KOCOSS) cohort. The results of the 6MWT performed at enrollment were analyzed in this study. A total of 1789 participants performed the 6MWT. Among them, 185 (10.3%) experienced desaturation during 6MWT. Old age, ex-smoker, low forced expiratory volume in one second (%), and high COPD assessment test score were significantly associated with exertional desaturation.

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Publication Details

Journal
International Journal of COPD
Published
2025-08-01
DOI
https://doi.org/10.2147/copd.s522341
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
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article

Factors Associated with Exertional Desaturation in Patients with Chronic Obstructive Pulmonary Disease

Seong Yong Lim, Kwang Ha Yoo, Chin Kook Rhee, Chang Youl Lee et al.
1 links
International Journal of COPD
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Factors Associated with Exertional Desaturation in Patients with Chronic Obstructive Pulmonary Disease

Seong Yong Lim, Kwang Ha Yoo, Chin Kook Rhee, Chang Youl Lee, Seung Ju Kim, Hyoung Kyu Yoon, Soo‐Jung Um, Deog Kyeom Kim, Yong Bum Park, Won‐Yeon Lee
article en

Abstract

The six minute walk test (6MWT) has a prognostic role in patients with chronic obstructive pulmonary disease (COPD). The aim of this study was to determine the factors associated with desaturation during the 6MWT in patients with COPD. This study utilized data from the prospective KOrea COPD Subgroup Study (KOCOSS) cohort. The results of the 6MWT performed at enrollment were analyzed in this study. A total of 1789 participants performed the 6MWT. Among them, 185 (10.3%) experienced desaturation during 6MWT. Old age, ex-smoker, low forced expiratory volume in one second (%), and high COPD assessment test score were significantly associated with exertional desaturation.

International Journal of COPDVol. Volume 20
Seoul National University (KR), Hallym University (KR), Yonsei University (KR), Dong-A University Hospital (KR), Seoul Metropolitan Government (KR), Konkuk University Medical Center (KR), SNUH SMG-SNU Boramae Medical Center (KR), Wonju Severance Christian Hospital (KR), Kangbuk Samsung Hospital (KR), The Catholic University of Korea Yeouido St. Mary's Hospital (KR), Kangdong Sacred Heart Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Hallym University Chuncheon Sacred Heart Hospital (KR), Catholic University of Korea (KR)
Gender equality
Openalex Percentile: Top 69%
Chronic Obstructive Pulmonary Disease (COPD) Research
DOIOpen Access PDFOpenAlex
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