Anti-TIF1-Gamma Autoantibodies-Positive Juvenile Dermatomyositis Associated With Interstitial Lung Disease: A Case Report

Juvenile dermatomyositis (JDM) is a rare autoimmune disease in children, characterized by muscle inflammation and skin manifestations. This case report describes a nine-year-old boy with JDM associated with anti-TIF1-γ antibodies and interstitial lung disease (ILD). The patient presented with progressive muscle weakness and characteristic skin lesions. Imaging confirmed ILD, and treatment with methylprednisolone pulses and rituximab resulted in significant improvement. This case emphasizes the need for pulmonary monitoring in JDM patients, regardless of antibody profile, and highlights the importance of personalized treatment approaches.