Integrated multi-omics analysis identifies TPX2 as a potential prognostic and immunological biomarker in hepatocellular carcinoma
TPX2 is a key driver of proliferation and immune evasion in HCC, potentially serving as a diagnostic and prognostic biomarker to guide treatment strategies involving mitotic- or immune-based therapies.
Authors
- Yongpeng Wei
- Jianing Yuan
- Hui Peng
- Xinbo Liu (ORCID: https://orcid.org/0000-0001-7576-0061)
- Yu Wang (ORCID: https://orcid.org/0009-0009-5160-4449)
Institutions
- Second Military Medical University (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- The Central Hospital of Enshi Tujia and Miao Autonomous Prefecture (CN)
- Yueyang Hospital (CN)
- Eastern Hepatobiliary Surgery Hospital (CN)
Publication Details
- Journal
- iLiver
- Published
- 2025-08-12
- DOI
- https://doi.org/10.1016/j.iliver.2025.100184
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00