Diagnostic Value of Image-Guided Percutaneous Omental, Peritoneal, and Mesenteric Biopsy: A Single-Center Study in a Tertiary Care Hospital in India

Abstract The purpose was to assess the technique, technical success rate, and diagnostic value of image-guided percutaneous biopsy of omental, peritoneal, and mesenteric lesions. This was a combined prospective and retrospective study conducted at our center from January 2019 to April 2021. Retrospective data were obtained by retrospective review of the institutional database from January 2017 to January 2019. For the prospective data, all patients referred to the interventional radiology department for image-guided peritoneal, omental, or mesenteric biopsy during the study period were included in the study. Patients not willing to participate in the study, cases lost to follow-up, and those in whom imaging data could not be retrieved in the picture archiving and communication system were excluded from the study. A total of 207 patients who underwent computed tomography-guided biopsies were the final study cohort, including 134 prospective cases and 73 retrospective cases. Various technical aspects, like technical success rate, diagnostic yield, and diagnostic performance of the procedure, were calculated and tabulated. The technical success rate and diagnostic yield of all biopsies were 100 and 98.06%, respectively. The overall sensitivity, specificity, positive predictive value, and negative predictive value of all biopsies to diagnose pathology were found to be 84.62, 91.46, 70.21, and 96.15%, respectively, while the accuracy to detect malignant pathology was 90.15%. The image-guided percutaneous biopsy of omental, mesenteric, and peritoneal lesions has a high technical success rate and diagnostic yield irrespective of lesion size and lesion depth.