The challenge of secondary cardiovascular prevention in very high Lipoprotein (a) level: a case report
Three critical aspects of daily practice emerge from our observation. First, Lp(a) is a valuable parameter for CV risk stratification in primary prevention. Second, measurement of Lp(a) post-CV event may provide valuable information on the risk of ischaemic recurrence, influencing decisions regarding long-term dual anti-platelet therapy (DAPT). Finally, this case illustrates the importance of a multidisciplinary approach in managing patients with very high cardiovascular risk. Close collaboration between cardiologists and lipidologists facilitated the identification of a rare lipid disorder and the decision to pursue lipoprotein apheresis, an intensive but effective treatment option for lipid metabolism disorders lacking conventional medical therapy.
Authors
- Andrea D’Amuri (ORCID: https://orcid.org/0000-0002-7421-0014)
- Corrado Lettieri
- Mauro Pagani (ORCID: https://orcid.org/0000-0002-0591-5416)
- Pietro Di Gangi
Institutions
- Azienda Ospedaliera Carlo Poma (IT)
Publication Details
- Journal
- European Heart Journal - Case Reports
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1093/ehjcr/ytaf389
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00