The challenge of secondary cardiovascular prevention in very high Lipoprotein (a) level: a case report

Three critical aspects of daily practice emerge from our observation. First, Lp(a) is a valuable parameter for CV risk stratification in primary prevention. Second, measurement of Lp(a) post-CV event may provide valuable information on the risk of ischaemic recurrence, influencing decisions regarding long-term dual anti-platelet therapy (DAPT). Finally, this case illustrates the importance of a multidisciplinary approach in managing patients with very high cardiovascular risk. Close collaboration between cardiologists and lipidologists facilitated the identification of a rare lipid disorder and the decision to pursue lipoprotein apheresis, an intensive but effective treatment option for lipid metabolism disorders lacking conventional medical therapy.

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Publication Details

Journal
European Heart Journal - Case Reports
Published
2025-08-09
DOI
https://doi.org/10.1093/ehjcr/ytaf389
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
0.00
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article

The challenge of secondary cardiovascular prevention in very high Lipoprotein (a) level: a case report

Andrea D’Amuri, Corrado Lettieri, Mauro Pagani, Pietro Di Gangi
European Heart Journal - Case Reports
Lipoproteins and Cardiovascular Health
article

The challenge of secondary cardiovascular prevention in very high Lipoprotein (a) level: a case report

Andrea D’Amuri, Corrado Lettieri, Mauro Pagani, Pietro Di Gangi
article en

Abstract

Three critical aspects of daily practice emerge from our observation. First, Lp(a) is a valuable parameter for CV risk stratification in primary prevention. Second, measurement of Lp(a) post-CV event may provide valuable information on the risk of ischaemic recurrence, influencing decisions regarding long-term dual anti-platelet therapy (DAPT). Finally, this case illustrates the importance of a multidisciplinary approach in managing patients with very high cardiovascular risk. Close collaboration between cardiologists and lipidologists facilitated the identification of a rare lipid disorder and the decision to pursue lipoprotein apheresis, an intensive but effective treatment option for lipid metabolism disorders lacking conventional medical therapy.

European Heart Journal - Case ReportsVol. 9(9)
Azienda Ospedaliera Carlo Poma (IT)
Openalex Percentile: Top 66%
Lipoproteins and Cardiovascular Health
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