A J-aggregating cyanine-based NIR-II optical sensor for DNA aptamer-mediated detection and imaging of quinine

We report a dye-displacement assay for quinine detection integrating a DNA aptamer with a J-aggregating NIR-II cyanine dye. This platform achieves sensitive, selective, and label-free NIR-II colorimetric and fluorescence sensing, with a fluorescence-based detection limit as low as 0.014 μM in urine solution, and enables NIR-II fluorescence imaging.

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Publication Details

Journal
Chemical Communications
Published
2025-01-01
DOI
https://doi.org/10.1039/d5cc03180j
Citations
3
Primary Topic
Advanced biosensing and bioanalysis techniques
Type
article
Field-Weighted Citation Impact
2.42
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article

A J-aggregating cyanine-based NIR-II optical sensor for DNA aptamer-mediated detection and imaging of quinine

Jiawei Chen, Shuizhu Wu, Chaobang Zhang, Zeng Fang et al.
3 citations
Chemical Communications
Advanced biosensing and bioanalysis techniques
2.42
article

A J-aggregating cyanine-based NIR-II optical sensor for DNA aptamer-mediated detection and imaging of quinine

Jiawei Chen, Shuizhu Wu, Chaobang Zhang, Zeng Fang, Gaowei Deng
article en
3 citations

Abstract

We report a dye-displacement assay for quinine detection integrating a DNA aptamer with a J-aggregating NIR-II cyanine dye. This platform achieves sensitive, selective, and label-free NIR-II colorimetric and fluorescence sensing, with a fluorescence-based detection limit as low as 0.014 μM in urine solution, and enables NIR-II fluorescence imaging.

Chemical CommunicationsVol. 61(74)
State Key Laboratory of Luminescent Materials and Devices, South China University of Technology (CN)
Openalex Percentile: Top 11%
Advanced biosensing and bioanalysis techniques
2.42
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