Effects of respiratory muscle training on psychological status and physical health of depression with sleep disorders in radiotherapy for lung cancer

Recent years have seen a growing incidence of lung cancer (LC). This study explored the effect of respiratory muscle training (RMT) combined with vitamin B6 on patients with depression combined with sleep disorders (DSD). By comparing the Pittsburgh sleep quality index (PSQI), self-rating anxiety scale (SAS)/self-rating depression scale (SDS) of the three groups of DSD patients who received conventional rehabilitation training (n = 54), the control group who received conventional rehabilitation training combined with vitamin B6 (n = 47), and the combined group who received RMT combined with vitamin B6 (n = 65), we found that the Pittsburgh sleep quality index (PSQI), the self-rating anxiety scale (SAS)/self-rating depression scale (SDS) of the combined group were significantly lower than the PSQI. scale (SAS)/self-rating depression scale (SDS) and Clinical frailty scale (CFS) in the three groups of DSD patients, and we found that the sleep disorder, psychological status and cancer-related fatigue in the combined group were more significantly improved (P < 0.05). Meanwhile, the nutritional status of the combined group after treatment was also more favorable than the other two groups (P < 0.05). Finally, through one-year prognostic follow-up, we found that although there was no difference in prognostic survival rate and tumor recurrence rate among the three groups (P > 0.05), the Mandarin Chinese version of the Leicester Cough Questionnaire (LCQ-MC) score was higher in the combined group (P < 0.05). These results suggest that RMT combined with vitamin B6 can lay a more reliable foundation for the prognosis and rehabilitation of patients with DSD.