Comparing burden of ischemic stroke caused by high low-density lipoprotein cholesterol in global and China: trends and projections
Despite declines in age-standardized rates, the absolute burden of IS attributable to high LDL-C continues to rise globally, driven by population aging and growth. China, in particular, faces a disproportionately higher burden compared to global trends, with slower progress in reducing these rates. Significant age- and sex-based disparities remain. These findings underscore the urgent need for targeted public health strategies to address the growing burden of IS, particularly in China, by focusing on effective LDL-C management.
Authors
- Jianghong Yue (ORCID: https://orcid.org/0009-0001-5554-7199)
- Mingxiu Liu (ORCID: https://orcid.org/0000-0003-3998-0491)
- Jie Yang (ORCID: https://orcid.org/0000-0002-5243-0534)
- Liang Zuo (ORCID: https://orcid.org/0000-0003-2971-3701)
- Enli Cai (ORCID: https://orcid.org/0000-0002-9916-1829)
- Gao Liu (ORCID: https://orcid.org/0000-0002-9025-3751)
- Jiali Zhang (ORCID: https://orcid.org/0009-0005-7478-8982)
- Qiang Xu (ORCID: https://orcid.org/0009-0006-0491-467X)
Institutions
- Yunnan University (CN)
- Haikou City People's Hospital (CN)
- Second People's Hospital of Yunnan Province (CN)
- Yunnan Provincial Hospital of Traditional Chinese Medicine (CN)
- Kunming Municipal Hospital of Traditional Chinese Medicine (CN)
- Yunnan University of Traditional Chinese Medicine (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fneur.2025.1622361
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00