Distinct NK cell function and gene expression in children with acute lymphoblastic leukemia in remission before and after acute exercise: an exploratory study
Acute exercise may improve NK cell function in ALL children in remission and has the potential to be used as adjunctive therapy in ALL. The differential gene expression response to exercise suggests that NK cells in ALL may adopt a different molecular strategy to fight infections or tumors.
Authors
- Ronen Bar‐Yoseph (ORCID: https://orcid.org/0000-0002-0055-5415)
- Abel Plaza‐Florido (ORCID: https://orcid.org/0000-0002-5374-3129)
- Dan M. Cooper (ORCID: https://orcid.org/0000-0003-4022-0043)
- Shlomit Radom‐Aizik (ORCID: https://orcid.org/0009-0004-4023-7026)
- Martin Perlsteyn
- Alejandro Lucía (ORCID: https://orcid.org/0000-0002-5565-0997)
- Fadia Haddad
Institutions
- University of California, Irvine (US)
- Research Institute Hospital 12 de Octubre (ES)
- Rappaport Family Institute for Research in the Medical Sciences (IL)
- Universidad Europea de Madrid (ES)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1625437
- Primary Topic
- Childhood Cancer Survivors' Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 0.00