Integrated analysis of single cell and spatial transcriptomics revealed a metastasis mechanism mediated by fatty acid metabolism in lymph nodes of head and neck cancer
This study described metabolic changes during HNSCC dissemination and revealed the critical role of metastatic tumors in the mechanism of HNSCC metastasis by regulating fatty acid metabolism.
Authors
- Jiajie Mao
- Xiaolin Nong
- Yixing Li (ORCID: https://orcid.org/0000-0002-1419-6142)
- Zhao Jun (ORCID: https://orcid.org/0000-0002-6691-2999)
- Jinru Weng
Institutions
- Guangxi Medical University (CN)
- Zhejiang Cancer Hospital (CN)
- Zhejiang University Medical College Affiliated Stomatological Hospital (CN)
- Yiwu Science and Technology Research Institute (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1614498
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Division of Graduate Education