Molecular characterization and prognostic modeling associated with M2-like tumor-associated macrophages in breast cancer: revealing the immunosuppressive role of DLG3
We constructed and comprehensively solved a model of M2-like TAM-related molecular subtypes and prognosis, which helps stratify and customize treatment regimens for BC patients. We also explored the role of <i>DLG3</i> in BC progression and macrophage polarization.
Authors
- Chaoqun Lian (ORCID: https://orcid.org/0000-0003-4914-020X)
- Jing Zhang (ORCID: https://orcid.org/0000-0001-6438-9113)
- Kai Zhang (ORCID: https://orcid.org/0000-0003-4242-0866)
- Qiang Zhang (ORCID: https://orcid.org/0000-0002-0836-0970)
- Ziqiang Wang (ORCID: https://orcid.org/0000-0001-9785-9222)
- Hongyu Ma (ORCID: https://orcid.org/0000-0002-8689-5970)
- Huili Chen
- Hongtao Wang (ORCID: https://orcid.org/0000-0002-8677-3164)
- Feiyue Zhang (ORCID: https://orcid.org/0000-0002-1057-9082)
- Min Lu (ORCID: https://orcid.org/0000-0003-0636-2240)
- Linfeng Pan (ORCID: https://orcid.org/0000-0003-0398-7333)
- Yiluo Xie
- Xinyu Zhang (ORCID: https://orcid.org/0000-0002-0273-9015)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Xiamen University (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Origin Quantum Computing Technology Company (China) (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1650726
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80