Detection of viral contamination in cell lines using ViralCellDetector
Our mapping-based approach enables robust detection of viral contamination in RNA-seq data from any host organism, while the marker-based approach accurately identifies viral infections specifically in human cell lines. This capability can help researchers detect and avoid the use of contaminated cell lines, thereby improving the reliability of experimental outcomes.
Authors
- Rama Shankar (ORCID: https://orcid.org/0000-0002-7115-4694)
- Shreya Paithankar (ORCID: https://orcid.org/0000-0002-9247-7847)
- Bin Chen (ORCID: https://orcid.org/0000-0001-8858-874X)
- Suchir Gupta
Institutions
- Michigan State University (US)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fmicb.2025.1595180
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00