Case Report: Immune-related eruptive keratoacanthoma with fungal coinfection under PD-1 inhibitor therapy: a diagnostic and therapeutic challenge
This is the first documented case of eruptive KA linked to zimberelimab, expanding the spectrum of PD-1 inhibitor-associated ircAEs. A concurrent fungal infection obscured the diagnosis, delaying appropriate treatment and highlighting the importance of recognizing rare ircAEs and multidisciplinary collaboration.
Authors
- Hou‐Wen Lin (ORCID: https://orcid.org/0000-0002-7097-0876)
- Zhenhua Wu (ORCID: https://orcid.org/0000-0003-4552-883X)
- Xiumei Ma (ORCID: https://orcid.org/0000-0002-6881-1534)
- Mengxia Yan (ORCID: https://orcid.org/0000-0001-5954-019X)
- Yanli Hou (ORCID: https://orcid.org/0000-0002-6371-6933)
- Ying-Jie Su
Institutions
- Shanghai Jiao Tong University (CN)
- Renji Hospital (CN)
- Ningbo No. 2 Hospital (CN)
- Ningbo No.6 Hospital (CN)
- Ningbo First Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fphar.2025.1619450
- Primary Topic
- Nonmelanoma Skin Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00