Study on the relationship between lid-parallel conjunctival folds and symptoms and signs of dry eye disease

A significant negative correlation was found between the grade of temporal side LIPCOF and the FBUT in all 76 eyes, both in the aqueous deficiency group and the non-aqueous deficiency group. Similarly, temporal side LIPCOF showed a reliable positive correlation with dry eye disease severity grading in the non-aqueous deficiency group. However, this correlation was not statistically significant in the aqueous deficiency group. For the grade of nasal side LIPCOF, there was no statistical correlation between the conjunctival fold grade and the FBUT in all 76 eyes. However, there was a significant positive correlation between the conjunctival fold grade and the FBUT in the aqueous deficiency group. In the non-aqueous deficiency group, there was a significant negative correlation between the conjunctival fold grade and FBUT. For the total number of LIPCOFs, there was no statistical correlation between the total number of LIPCOFs and FBUT in all 76 eyes and the aqueous deficiency group. However, there was a significant negative correlation between the total number of LIPCOFs and FBUT in the non-aqueous deficiency group.