A comparative analysis of cardiopulmonary features in patients with systemic sclerosis and mixed connective tissue disease: results from SOPHIE registry
In this cross-sectional analysis, we found small airway dysfunction in patients with SSc and impaired left ventricular systolic function in patients with MCTD. These findings indicate that there is significant heterogeneity in the cardiopulmonary involvement patterns, although these patterns are both connective tissue diseases with similar disease duration and comorbidity burden.
Authors
- Chung‐Wah Siu (ORCID: https://orcid.org/0000-0002-2666-3086)
- Jing Yuan Tan (ORCID: https://orcid.org/0000-0001-5770-4701)
- Cecilia Wong (ORCID: https://orcid.org/0000-0003-2375-8474)
- Wenjun Zhang (ORCID: https://orcid.org/0000-0002-4497-0688)
- Lixue Yin (ORCID: https://orcid.org/0000-0002-5051-147X)
- Rui Yang (ORCID: https://orcid.org/0000-0003-1801-6134)
- Binghua Wang
- Mingrui Liao
- Mi Zhou
Institutions
- University of Electronic Science and Technology of China (CN)
- Queen Mary Hospital (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fmed.2025.1626546
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Sichuan Province Science and Technology Support Program
- Chengdu Science and Technology Program