Case Report: Mycobacterium abscessus knee joint infection following herbal steam bath: successful short-course oral therapy in an immunocompetent patient
Review of 20 MABC joint infection cases from the literature revealed the knee as the most frequently affected site (55%), with the majority of patients (95%) having a history of joint surgery. This case highlights: 1) Herbal steam therapy, degenerative joint disease, and prior interventions as underrecognized risk factors; 2) Rapid molecular diagnostics (MALDI-TOF MS/<i>hsp65</i>) critical for early diagnosis; 3) Short-course oral therapy (clarithromycin/linezolid) as a potential option for localized infection when prolonged therapy is impractical.
Authors
- Cuiying Zheng
- L P Zhang (ORCID: https://orcid.org/0009-0003-6858-409X)
- Minghui Song (ORCID: https://orcid.org/0000-0002-0570-0124)
- Jiaqing Ye
- Weili Gao
- Yumei Guo
- Chenfeng Zhang
- Jiahao Hao
Institutions
- Hebei Medical University (CN)
- Zhejiang Chinese Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- Jiaxing University (CN)
- First Hospital of Jiaxing (CN)
- Hebei Provincial Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fimmu.2025.1618830
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Hebei Province