Case Report: Mycobacterium abscessus knee joint infection following herbal steam bath: successful short-course oral therapy in an immunocompetent patient

Review of 20 MABC joint infection cases from the literature revealed the knee as the most frequently affected site (55%), with the majority of patients (95%) having a history of joint surgery. This case highlights: 1) Herbal steam therapy, degenerative joint disease, and prior interventions as underrecognized risk factors; 2) Rapid molecular diagnostics (MALDI-TOF MS/<i>hsp65</i>) critical for early diagnosis; 3) Short-course oral therapy (clarithromycin/linezolid) as a potential option for localized infection when prolonged therapy is impractical.

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Journal
Frontiers in Immunology
Published
2025-08-13
DOI
https://doi.org/10.3389/fimmu.2025.1618830
Primary Topic
Mycobacterium research and diagnosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Case Report: Mycobacterium abscessus knee joint infection following herbal steam bath: successful short-course oral therapy in an immunocompetent patient

Cuiying Zheng, L P Zhang, Minghui Song, Jiaqing Ye et al.
Frontiers in Immunology
Mycobacterium research and diagnosis
article

Case Report: Mycobacterium abscessus knee joint infection following herbal steam bath: successful short-course oral therapy in an immunocompetent patient

Cuiying Zheng, L P Zhang, Minghui Song, Jiaqing Ye, Weili Gao, Yumei Guo, Chenfeng Zhang, Jiahao Hao
article en

Abstract

Review of 20 MABC joint infection cases from the literature revealed the knee as the most frequently affected site (55%), with the majority of patients (95%) having a history of joint surgery. This case highlights: 1) Herbal steam therapy, degenerative joint disease, and prior interventions as underrecognized risk factors; 2) Rapid molecular diagnostics (MALDI-TOF MS/<i>hsp65</i>) critical for early diagnosis; 3) Short-course oral therapy (clarithromycin/linezolid) as a potential option for localized infection when prolonged therapy is impractical.

Frontiers in ImmunologyVol. 16
Hebei Medical University (CN), Zhejiang Chinese Medical University (CN), Third Hospital of Hebei Medical University (CN), Jiaxing University (CN), First Hospital of Jiaxing (CN), Hebei Provincial Center for Disease Control and Prevention (CN)
Natural Science Foundation of Hebei Province
Openalex Percentile: Top 71%
Mycobacterium research and diagnosis
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Case Report: Mycobacterium abscessus knee joint infection following herbal steam bath: successful short-course oral therapy in an immunocompetent patient — Cuiying Zheng, L P Zhang, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS