A laminin-based therapy for dogs with chronic spinal cord injury: promising results of a longitudinal trial
Although the present study could not discriminate between the benefits of the two treatments, our findings suggest that polylaminin, in combination with GDNF or chondroitinase ABC, is a safe and potentially effective treatment, which underscores the relevance of further studies to establish a new approach to improving gait function in dogs with chronic SCI.
Authors
- Tatiana Coelho‐Sampaio (ORCID: https://orcid.org/0000-0002-3020-9580)
- David Vivas (ORCID: https://orcid.org/0000-0003-0034-4375)
- Karla Menezes (ORCID: https://orcid.org/0000-0002-4343-5587)
- M Freire
- Paulo Roberto Louzada
- Aurélio V. Graça-Souza
- Carolina de Miranda Chize
- Rodrigo Ferreira Pinto Jiddu
- Eliel de Souza-Leite
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- Estácio (Brazil) (BR)
Publication Details
- Journal
- Frontiers in Veterinary Science
- Published
- 2025-08-13
- DOI
- https://doi.org/10.3389/fvets.2025.1592687
- Citations
- 1
- Primary Topic
- Veterinary Orthopedics and Neurology
- Type
- article
- Field-Weighted Citation Impact
- 2.35