Meningococcal Septic Shock Revealed: The Frightening Face of Serogroup B

Meningococcal infections are still a serious cause of morbidity and mortality in children, despite vaccine developments or advancements in vaccination, antibiotics, supportive treatments, and advancements in intensive care facilities. <i>Neisseria meningitidis</i> has 12 serogroups, among which A, B, C, Y, and W are responsible for the most invasive infections. Sudden onset, rapid worsening, and high contagiousness are important clinical features of meningococcal infections. Purpura fulminans, septic shock, multiple organ failure, and increased intracranial pressure also constitute life-threatening complications. Here, we present a six-month-old female patient who presented with complaints of fever, malaise, and rash and was diagnosed with meningococcal sepsis and shock based on clinical examination, laboratory findings, and blood polymerase chain reaction (PCR) positivity. She was treated in the pediatric intensive care unit (PICU) but died despite the treatments.

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Publication Details

Journal
Cureus
Published
2025-08-12
DOI
https://doi.org/10.7759/cureus.89950
Primary Topic
Bacterial Infections and Vaccines
Type
article
Field-Weighted Citation Impact
0.00
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article

Meningococcal Septic Shock Revealed: The Frightening Face of Serogroup B

Ergi̇n Çi̇ftçi̇, Merve Havan, Halil Özdemir, Zeynep Ceren Karahan et al.
Cureus
Bacterial Infections and Vaccines
article

Meningococcal Septic Shock Revealed: The Frightening Face of Serogroup B

Ergi̇n Çi̇ftçi̇, Merve Havan, Halil Özdemir, Zeynep Ceren Karahan, Selin Nar Ötgün, Tanıl Kendirli, Döndü Nilay Penezoğlu, Ebru Evren, Belkis Hatice Inceli
article en

Abstract

Meningococcal infections are still a serious cause of morbidity and mortality in children, despite vaccine developments or advancements in vaccination, antibiotics, supportive treatments, and advancements in intensive care facilities. <i>Neisseria meningitidis</i> has 12 serogroups, among which A, B, C, Y, and W are responsible for the most invasive infections. Sudden onset, rapid worsening, and high contagiousness are important clinical features of meningococcal infections. Purpura fulminans, septic shock, multiple organ failure, and increased intracranial pressure also constitute life-threatening complications. Here, we present a six-month-old female patient who presented with complaints of fever, malaise, and rash and was diagnosed with meningococcal sepsis and shock based on clinical examination, laboratory findings, and blood polymerase chain reaction (PCR) positivity. She was treated in the pediatric intensive care unit (PICU) but died despite the treatments.

CureusVol. 17(8)
Ankara University (TR), Public Health Agency (GB)
Zero hunger
Openalex Percentile: Top 81%
Bacterial Infections and Vaccines
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