A Promising TNF-<i>α</i> Inhibition Activity of 2-Aminocyclopentenylphosphonates

Buoyed by our previous TNF-α results, three 2-amino-1-cyclopentenylphos-phonate compounds which were synthesized by the reaction of diethyl 5-chloro-1-pentynylphosphonate with various amines exhibited promising TNF-α inhibitory activity.

Authors

Publication Details

Journal
Journal of Biosciences and Medicines
Published
2025-01-01
DOI
https://doi.org/10.4236/jbm.2025.138012
Primary Topic
Synthesis and biological activity
Type
article
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article

A Promising TNF-α Inhibition Activity of 2-Aminocyclopentenylphosphonates

Abed Al Aziz Al Quntar, Imad Matouk, Ibrahim Abasy, Mira Shatat
Journal of Biosciences and Medicines
Synthesis and biological activity
article

A Promising TNF-α Inhibition Activity of 2-Aminocyclopentenylphosphonates

Abed Al Aziz Al Quntar, Imad Matouk, Ibrahim Abasy, Mira Shatat
article en

Abstract

Buoyed by our previous TNF-α results, three 2-amino-1-cyclopentenylphos-phonate compounds which were synthesized by the reaction of diethyl 5-chloro-1-pentynylphosphonate with various amines exhibited promising TNF-α inhibitory activity.

Journal of Biosciences and MedicinesVol. 13(08)
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Synthesis and biological activity
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A Promising TNF-<i>α</i> Inhibition Activity of 2-Aminocyclopentenylphosphonates — Abed Al Aziz Al Quntar, Imad Matouk, et al. · Journal of Biosciences and Medicines (2025) | TGRS Research Map | TGRS