Integration of metabolic and bioprocess engineering for the production of β-ketoadipic acid from glucose and xylose by <i>Pseudomonas putida</i>
β-Ketoadipic acid, an intermediate in aerobic microbial aromatic catabolism suitable as a monomer in performance-advantaged biopolymers, was produced at a high titer, rate, and yield from glucose and xylose in P. putida with in situ product recovery.
Authors
- Gregg T. Beckham (ORCID: https://orcid.org/0000-0002-3480-212X)
- Morgan A. Ingraham (ORCID: https://orcid.org/0000-0002-7350-4862)
- Davinia Salvachúa (ORCID: https://orcid.org/0000-0003-0799-061X)
- Sekgetho Charles Mokwatlo (ORCID: https://orcid.org/0000-0003-2617-0019)
- Kelsey J. Ramirez (ORCID: https://orcid.org/0000-0002-5114-742X)
- Gabriel M. Rubinstein (ORCID: https://orcid.org/0000-0002-8257-212X)
- Patrick O. Saboe (ORCID: https://orcid.org/0000-0003-3605-5145)
- Christopher W. Johnson (ORCID: https://orcid.org/0000-0002-2979-4751)
- Louis A. Chirban
- Hoon Choi (ORCID: https://orcid.org/0000-0002-2791-3788)
- Ariel R. Lepard (ORCID: https://orcid.org/0009-0007-2070-9171)
Institutions
- National Laboratory of the Rockies (US)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5gc01813g
- Citations
- 1
- Primary Topic
- Biofuel production and bioconversion
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- Bioenergy Technologies Office
- National Renewable Energy Laboratory