Effect of Nursing Instructions on Knowledge and Therapeutic Adherence among Leukemic Patients Undergoing Bone Marrow Transplantation.

Leukemia is a heterogeneous group of hematologic malignancies that arise from the dysfunctional of developing leukocytes. Bone marrow transplantation used to replace bone marrow cells which damaged by disease or chemotherapy with healthy cells. Therapeutic adherence is the extent to which patients take medication as prescribed by their doctors, failure of therapeutic adherence lead to poor health outcomes Aim: to evaluate the effect of nursing instructions on knowledge and therapeutic adherence among leukemic patients undergoing bone marrow transplantation. Methods: Quasi-experimental design was utilized. Subjects: A purposive sample of 70 patients with leukemia undergoing BMT, Setting: bone marrow transplantation units at Nasser Institute for Research and Treatment. Tools: Three tools were used. Tool (I): Patient`s structured Interview Questionnaire. Tool (II): Patient`s therapeutic adherence. Tool (III): Patients’ adherence to healthy life style. Results: The study showed highly statistically significant improvement in leukemic patient`s knowledge and therapeutic adherence among the studied patients immediately post and six months after implementation of nursing instructions as compared to pre implementation of instructions. In addition, the present study revealed that there was negative correlation between total patients’ knowledge score and total therapeutic adherence barriers score at pre , immediately post and six months after implementation of nursing instructions. Conclusion: Implementation of nursing instructions have appositive effect in improving studied patient ’knowledge and therapeutic adherence among leukemic patients undergoing BMT. Recommendation: