Causal Associations of the Alterations in Peripheral Blood Immune Cell Characteristics on the Incidence of Osteoporosis: A Bidirectional Mendelian Randomization Study
This study identified a unidirectional causal link between five immune cell traits and osteoporosis, providing new insights into osteoporosis pathogenesis and potential targeted immunotherapy.
Authors
- Wai Leung Ambrose Lo (ORCID: https://orcid.org/0000-0001-7350-2157)
- Siyun Zhang (ORCID: https://orcid.org/0000-0003-4087-6595)
- Qiuhua Yu
- Kai Li (ORCID: https://orcid.org/0000-0002-6683-517X)
- Minghui Ding (ORCID: https://orcid.org/0000-0003-4715-9302)
- Qunhui Yin
- Chuhuai Wang (ORCID: https://orcid.org/0000-0002-8071-9298)
- Xin Li (ORCID: https://orcid.org/0000-0002-5890-0373)
- Rong Chen (ORCID: https://orcid.org/0000-0002-6716-0071)
Institutions
- Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- Therapeutics and Clinical Risk Management
- Published
- 2025-08-01
- DOI
- https://doi.org/10.2147/tcrm.s518164
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00