Co-Radiotherapy with Tyrosine Kinase Inhibitors Might Benefit Survival in Hepatoma Patients with Portal Vein Tumor Thrombosis

In this series, 26.9% (43/160) of HCC patients with PVTT underwent combination treatment with TKIs and RT, achieving a median survival of 15.0 months. The contributions of RT were 20% disease control rate and may extend the duration of TKIs use. Therefore, all candidates without contraindications should be considered for combination treatment.

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Publication Details

Journal
Biomedical Journal
Published
2025-08-01
DOI
https://doi.org/10.1016/j.bj.2025.100904
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
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article

Co-Radiotherapy with Tyrosine Kinase Inhibitors Might Benefit Survival in Hepatoma Patients with Portal Vein Tumor Thrombosis

Sheng‐Nan Lu, Te‐Sheng Chang, Wei-Ming Lin, Chia‐Hsuan Lai et al.
1 links
Biomedical Journal
Hepatocellular Carcinoma Treatment and Prognosis
article

Co-Radiotherapy with Tyrosine Kinase Inhibitors Might Benefit Survival in Hepatoma Patients with Portal Vein Tumor Thrombosis

Sheng‐Nan Lu, Te‐Sheng Chang, Wei-Ming Lin, Chia‐Hsuan Lai, Hui‐Ling Huang
article en

Abstract

In this series, 26.9% (43/160) of HCC patients with PVTT underwent combination treatment with TKIs and RT, achieving a median survival of 15.0 months. The contributions of RT were 20% disease control rate and may extend the duration of TKIs use. Therefore, all candidates without contraindications should be considered for combination treatment.

Biomedical Journal
Kaohsiung Chang Gung Memorial Hospital (TW), Chiayi Chang Gung Memorial Hospital (TW)
Openalex Percentile: Top 71%
Hepatocellular Carcinoma Treatment and Prognosis
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