Use of Intrapleural Alteplase in the Treatment of Parapneumonic Effusion in Children: A Report of a 10-year Experience

Lower alteplase doses (≤2 mg) were effective for most children with PPE. Alteplase combined with primary VATS might be associated with better outcomes.

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Publication Details

Journal
The Journal of Pediatric Pharmacology and Therapeutics
Published
2025-08-01
DOI
https://doi.org/10.5863/jppt-24-00057
Primary Topic
Pleural and Pulmonary Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Use of Intrapleural Alteplase in the Treatment of Parapneumonic Effusion in Children: A Report of a 10-year Experience

Taylor Morrisette, Yusuf M. Garwan, Muath A. Alsalloum, A. Jill Thompson et al.
The Journal of Pediatric Pharmacology and Therapeutics
Pleural and Pulmonary Diseases
article

Use of Intrapleural Alteplase in the Treatment of Parapneumonic Effusion in Children: A Report of a 10-year Experience

Taylor Morrisette, Yusuf M. Garwan, Muath A. Alsalloum, A. Jill Thompson, Katherine Chessman
article en

Abstract

Lower alteplase doses (≤2 mg) were effective for most children with PPE. Alteplase combined with primary VATS might be associated with better outcomes.

The Journal of Pediatric Pharmacology and TherapeuticsVol. 30(4)
Medical University of South Carolina (US), Imam Abdulrahman Bin Faisal University (SA)
Good health and well-being
Openalex Percentile: Top 69%
Pleural and Pulmonary Diseases
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