Chemical Stability of Diphenhydramine in “Magic Mouthwash” Stored at Room and Refrigerated Temperatures for 90-Days
The pediatric "Magic Mouthwash" demonstrated stable pH and diphenhydramine potency over 90 days, regardless of whether it was stored at room temperature or refrigerated. This supports the feasibility of bulk preparation and extended storage of this formulation, providing a safe and effective alternative to lidocaine-containing mouthwash for pediatric patients.
Authors
- Kathryn E. Austin
- Stacy D. Brown (ORCID: https://orcid.org/0000-0001-5566-1728)
- Michelle Tubolino
- Daniel DeArazoza
Institutions
- East Tennessee State University (US)
- Miami Children's Hospital (US)
Publication Details
- Journal
- The Journal of Pediatric Pharmacology and Therapeutics
- Published
- 2025-08-01
- DOI
- https://doi.org/10.5863/jppt-24-00053
- Primary Topic
- Dental Anxiety and Anesthesia Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00