Study Effects of Nano Chitosan-Paracetemol to Inhibition Spread of Colon Cancer

One of the gastrointestinal system's most frequent malignant maximums is colon cancer. Currently, surgical resection is the main course of treatment. Nevertheless, colon cancer is prone to metastasis and recurrence, making the development of an efficient anti-cancer medication imperative. The present investigation employed FT-IR and 1HNMR technique’s to characterization of the synthesis and examination of nano Chitosan-Paracetemol composites. The cytotoxic potential of the new medicine (Nano Chitosan-Paracetemol composites) was evaluated, which had excellent results in our study, the number of infected cells decreased to (IC50=71.26 µg/ml). This work aimed to validate the cytotoxicity of nano Chitosan-Paracetemol on the colon cancer cell line HCT-29 as well as the efficacy of its reduction of metastasis of colon cancer.

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Publication Details

Journal
Journal of Kufa for Chemical Sciences
Published
2025-06-20
DOI
https://doi.org/10.36329/jkcm/2025/v4.i2.15418
Primary Topic
Synthesis of heterocyclic compounds
Type
article
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article

Study Effects of Nano Chitosan-Paracetemol to Inhibition Spread of Colon Cancer

Mohammad N. Al-Baiati, Heba A. Abd-Alsalam Alsalame, Ousama W. Abdulnabi
Journal of Kufa for Chemical Sciences
Synthesis of heterocyclic compounds
article

Study Effects of Nano Chitosan-Paracetemol to Inhibition Spread of Colon Cancer

Mohammad N. Al-Baiati, Heba A. Abd-Alsalam Alsalame, Ousama W. Abdulnabi
article en

Abstract

One of the gastrointestinal system's most frequent malignant maximums is colon cancer. Currently, surgical resection is the main course of treatment. Nevertheless, colon cancer is prone to metastasis and recurrence, making the development of an efficient anti-cancer medication imperative. The present investigation employed FT-IR and 1HNMR technique’s to characterization of the synthesis and examination of nano Chitosan-Paracetemol composites. The cytotoxic potential of the new medicine (Nano Chitosan-Paracetemol composites) was evaluated, which had excellent results in our study, the number of infected cells decreased to (IC50=71.26 µg/ml). This work aimed to validate the cytotoxicity of nano Chitosan-Paracetemol on the colon cancer cell line HCT-29 as well as the efficacy of its reduction of metastasis of colon cancer.

Journal of Kufa for Chemical SciencesVol. 4(2)
University of Kerala (IN), University of Kerbala (IQ)
Openalex Percentile: Top 85%
Synthesis of heterocyclic compounds
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Study Effects of Nano Chitosan-Paracetemol to Inhibition Spread of Colon Cancer — Mohammad N. Al-Baiati, Heba A. Abd-Alsalam Alsalame, et al. · Journal of Kufa for Chemical Sciences (2025) | TGRS Research Map | TGRS