Myocarditis, Myositis, and Myasthenia Gravis
If there is recent initiation of ICI therapy, elevated troponin, and concomitant ICI toxicities, providers should suspect ICI myocarditis despite negative cardiac magnetic resonance imaging. Nonsteroidal immunosuppression with CTLA-4 agonists may be effective in patients treated with CTLA-4 inhibitors.
Authors
- Blair Tilkens
- Sean Halloran
- Jon W. Lomasney (ORCID: https://orcid.org/0000-0002-0438-2427)
- A D Zubenko
- Joseph Alban
- Ruchi Patel (ORCID: https://orcid.org/0000-0001-9090-8423)
- Nisha Mohindra (ORCID: https://orcid.org/0000-0001-5913-1716)
- Nausheen Akhter (ORCID: https://orcid.org/0000-0001-9423-8578)
Institutions
- Northwestern University (US)
- Northwestern University (PH)
- Northwestern Medicine (US)
Publication Details
- Journal
- JACC Case Reports
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1016/j.jaccas.2025.104188
- Citations
- 2
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 2.09