Occurrence of coronary events in the absence of traditional risk factors: Understanding residual risk
Even in the absence of CVRFs, elevated triglycerides and hsCRP were significantly associated with an increased risk of CHD. These results highlight the importance of residual risk assessment using those biomarkers in individuals deemed metabolically healthy by conventional standards.
Authors
- Barbara Thorand (ORCID: https://orcid.org/0000-0002-8416-6440)
- Jean Ferrières (ORCID: https://orcid.org/0000-0001-6144-1297)
- H Tunstall-Pedoe
- Christina Magnussen (ORCID: https://orcid.org/0000-0002-5102-0955)
- Wolfgang Köenig (ORCID: https://orcid.org/0000-0002-2064-9603)
- Guido M. Grassi (ORCID: https://orcid.org/0000-0003-1922-6547)
- Philippe Amouyel (ORCID: https://orcid.org/0000-0001-9088-234X)
- Licia Iacoviello (ORCID: https://orcid.org/0000-0003-0514-5885)
- Sofia Malyutina (ORCID: https://orcid.org/0000-0001-6539-0466)
- Kari Kuulasmaa (ORCID: https://orcid.org/0000-0003-2165-1411)
- Alina Goßling (ORCID: https://orcid.org/0000-0002-5211-5593)
- Satu Männistö (ORCID: https://orcid.org/0000-0002-8668-3046)
- Tanja Zeller (ORCID: https://orcid.org/0000-0003-3379-2641)
- Stefan Söderberg (ORCID: https://orcid.org/0000-0001-9225-1306)
- Marie Moitry (ORCID: https://orcid.org/0000-0001-5196-8351)
- Allan Linneberg (ORCID: https://orcid.org/0000-0002-0994-0184)
- Francisco Ojeda (ORCID: https://orcid.org/0000-0003-4037-144X)
- Jessica Weimann
- Abdonas Tamošiūnas (ORCID: https://orcid.org/0000-0002-0868-457X)
- Veikko V Salomaa (ORCID: https://orcid.org/0000-0001-7563-5324)
- Hermann Brenner (ORCID: https://orcid.org/0000-0002-6129-1572)
- Natalie Arnold (ORCID: https://orcid.org/0000-0002-0809-8108)
- Wojciech Drygas (ORCID: https://orcid.org/0000-0002-4351-6459)
- Maurizio Ferrario (ORCID: https://orcid.org/0000-0003-2741-7124)
- Sameline Grimsgaard (ORCID: https://orcid.org/0000-0002-0601-0344)
- Renate B. Schnabel (ORCID: https://orcid.org/0000-0001-7170-9509)
- Giovanni Veronesi (ORCID: https://orcid.org/0000-0002-4119-6615)
- Stefan Blankenberg
- Luigi Palmieri
- Susana Sans
- Christoph Waldeyer
- Benjamin Bay
- F. Kee
Institutions
- University of Insubria (IT)
- Queen's University Belfast (GB)
- Lithuanian University of Health Sciences (LT)
- Inserm (FR)
- Generalitat de Catalunya (ES)
- Universität Hamburg (DE)
- University of Dundee (GB)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- Istituto Superiore di Sanità (IT)
- Institut Pasteur de Lille (FR)
- Frederiksberg Hospital (DK)
- Helmholtz Zentrum München (DE)
- Istituto Neurologico Mediterraneo (IT)
- Finnish Institute for Health and Welfare (FI)
- Research Institute of Therapy and Preventive Medicine (RU)
- University Medical Center Hamburg-Eppendorf (DE)
- Institute of Cytology and Genetics (RU)
- Medical University of Lodz (PL)
- Hôpital Rangueil (FR)
- German Centre for Cardiovascular Research (DE)
- Deutsches Herzzentrum München (DE)
- Hôpital Civil, Strasbourg (FR)
- University of Milano-Bicocca (IT)
- Université de Strasbourg (FR)
- UiT The Arctic University of Norway (NO)
- Ludwig-Maximilians-Universität München (DE)
- Umeå University (SE)
- University of Lübeck (DE)
Publication Details
- Journal
- Atherosclerosis
- Published
- 2025-08-09
- DOI
- https://doi.org/10.1016/j.atherosclerosis.2025.120475
- Citations
- 2
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Amgen
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- AstraZeneca
- Bayer
- Sanofi
- Foundation for Cardiovascular Research
- Deutsches Zentrum für Herz-Kreislaufforschung
- Medicines Company
- Kowa Company
- Singulex
- European Commission
- Bundesministerium für Bildung und Forschung
- Hjärt-Lungfonden
- Juho Vainion Säätiö
- Novo Nordisk
- Umeå Universitet
- Sydäntutkimussäätiö
- Deutsche Stiftung für Herzforschung
- Deutsche Herzstiftung
- Dr. Rolf M. Schwiete Stiftung
- Esperion Therapeutics
- Genentech
- Abbott Diagnostics
- Medical Research Council
- Daiichi Sankyo Europe