Trio exome analysis is a valuable tool for genetic diagnosis of epilepsy in Mali
Our findings illuminate a significant genetic contribution to epilepsy in Mali with a substantial genetic heterogeneity, as well as the utility of trio exome sequencing for efficient diagnosis. This further emphasizes the persistent and critical need for greater inclusivity in genomic research and implementation.
Authors
- Cheick Abdel Kader Cissé (ORCID: https://orcid.org/0000-0002-5845-9098)
- Abdoulaye Yalcouyé (ORCID: https://orcid.org/0000-0003-4279-7380)
- M Dembélé (ORCID: https://orcid.org/0009-0005-4332-5176)
- Aminata Touré (ORCID: https://orcid.org/0000-0001-5629-849X)
- Mahamadou Kotioumbé
- Ahmed Camara
- Guida Landouré (ORCID: https://orcid.org/0000-0002-5921-7832)
- Alassane Baneye Maīga (ORCID: https://orcid.org/0000-0002-7296-7785)
- Emily K. Mis
- Karamoko Nimaga
- Lassana Cissé (ORCID: https://orcid.org/0000-0001-6574-0956)
- Mamadou Traoré (ORCID: https://orcid.org/0000-0003-0558-1724)
- M Cisse
- Oumar Samassékou (ORCID: https://orcid.org/0000-0003-1916-4534)
- R. Kane
- Mustafa K. Khokha (ORCID: https://orcid.org/0000-0002-9846-7076)
- Weizhen Ji
- Modibo K. Goita (ORCID: https://orcid.org/0000-0002-8969-9529)
- Saquib A. Lakhani (ORCID: https://orcid.org/0000-0003-3235-3460)
- Salia Bamba (ORCID: https://orcid.org/0000-0002-1680-5183)
- Lauren Jeffries (ORCID: https://orcid.org/0000-0002-6419-0515)
- Samuel Ephrata Mefoung
- Salimata Diarra (ORCID: https://orcid.org/0000-0003-2160-9942)
- Oumou Traoré
- Seybou Hassane Diallo
- Amadou Touré
- Adama Koné
- Moussa Doumbia
- Mahamadou Traoré
- Cheick O. Guinto
- Moussa Sangaré
- Koudoussou Olaréwadjou Sanni
- Ibrahim Nimaga
Institutions
- Cedars-Sinai Medical Center (US)
- Yale University (US)
- University of Bamako (ML)
- Université des Sciences, des Techniques et des Technologies de Bamako (ML)
- Mali-Folkecenter (ML)
Publication Details
- Journal
- Genetics in Medicine Open
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.gimo.2025.103449
- Primary Topic
- RNA and protein synthesis mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fogarty International Center
- National Institute of Neurological Disorders and Stroke