Dendrosomal Curcumin Nanoformulation induces apoptosis via Bax/Bcl-2 in human ovarian cancer OVCAR3 cells
Our findings demonstrate that both DNC and Oxa induce apoptosis in OVCAR3 ovarian cancer cells through modulation of Bax and Bcl-2 expression. The enhanced efficacy observed in combination therapy highlights the therapeutic potential of DNC, in conjunction with conventional chemotherapeutics, as a promising strategy for ovarian cancer treatment.
Authors
- Elahe Seyed Hosseini (ORCID: https://orcid.org/0000-0001-9382-0822)
- Hamed Haddad Kashani (ORCID: https://orcid.org/0000-0003-2606-2886)
- Zahra Shabani (ORCID: https://orcid.org/0000-0003-4995-3024)
- Marziyeh Alizadeh Zarei
- Hossein Nikzad
Institutions
- Hamedan University of Medical Sciences (IR)
- Kashan University of Medical Sciences (IR)
Publication Details
- Journal
- Cancer Treatment and Research Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.ctarc.2025.100981
- Citations
- 1
- Primary Topic
- Curcumin's Biomedical Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.59