Identification of blaESBL- and blaCARBA- Positive Multi-Drug Resistant Mixta calida Isolates from Distinct Human Hosts
This study reports bla<sub>ESBL</sub> and bla<sub>CARBA</sub>-positive multi-drug resistant Mixta calida isolates from distinct human hosts. Genomic analysis revealed the co-occurrence of plasmid-borne resistance genes bla<sub>KPC-3</sub>, bla<sub>OXA-9</sub>, and bla<sub>TEM-122.</sub> Species-wide phylogenetic analysis grouped the two isolates into a monophyletic cluster, suggesting a single introductory event.
Authors
- Kate Ryan (ORCID: https://orcid.org/0000-0002-6903-9339)
- Francesca McDonagh (ORCID: https://orcid.org/0000-0002-0830-4899)
- Martin Cormican (ORCID: https://orcid.org/0000-0002-8023-1882)
- Georgios Miliotis (ORCID: https://orcid.org/0000-0002-0944-2206)
- Aneta Kovářová (ORCID: https://orcid.org/0009-0008-4812-1553)
- Anna Tumeo (ORCID: https://orcid.org/0009-0007-7689-2809)
- Christina Clarke
Institutions
- Ollscoil na Gaillimhe – University of Galway (IE)
- University Hospital Galway (IE)
Publication Details
- Journal
- International Journal of Medical Microbiology
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1016/j.ijmm.2025.151669
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Department of the Environment, Climate and Communications
- Environmental Protection Agency
- Irish Research Council for Science, Engineering and Technology
- Science Foundation Ireland