Somatosensory Profile of Central Post Stroke Pain of Thalamic Origin: Findings of a Quantitative Sensory Testing Study
Thalamic CPSP is very rare, thus our data contribute to the clinical and sensory phenotyping of patients suffering from this debilitating condition. We did not find abnormalities in thermal measures, but only mechanical thresholds in our cohort, suggesting that not only changes in temperature perception are necessary for the development of pain after thalamic stroke. Our findings suggest that a short QST protocol including mechanical testing using von Frey filaments and pin-prick-stimulators may be useful in the diagnosis of thalamic CPSP.
Authors
- Stefano Magon (ORCID: https://orcid.org/0000-0003-1517-7581)
- Priska Zuber (ORCID: https://orcid.org/0000-0001-6630-5980)
- Katarina Alexandra Ebner
- Shaumiya Sellathurai (ORCID: https://orcid.org/0009-0005-8609-0426)
- Till Sprenger (ORCID: https://orcid.org/0000-0002-5390-819X)
- Laura Gaetano (ORCID: https://orcid.org/0000-0002-5214-2858)
- Ludwig Kappos
- Athina Papadopoulou (ORCID: https://orcid.org/0000-0002-0367-1008)
- Lukas Enz (ORCID: https://orcid.org/0000-0002-6588-2142)
- Federico Burguet Villena (ORCID: https://orcid.org/0009-0009-9697-8364)
- Kean Schoenholzer (ORCID: https://orcid.org/0009-0004-7755-4447)
- Kristel Berati (ORCID: https://orcid.org/0009-0003-1932-227X)
Institutions
- Roche (Switzerland) (CH)
- Leiden University (NL)
- Novartis (Switzerland) (CH)
- University of Basel (CH)
- Leiden University Medical Center (NL)
- University Hospital of Basel (CH)
- University Hospital of Zurich (CH)
- Novartis Foundation (CH)
Publication Details
- Journal
- European Journal of Pain
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1002/ejp.70104
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung