Biological Ageing Acceleration and Functional Capacities Across the Lifespan in the INSPIRE‐T Cohort
Among four DNA methylation epigenetic clocks and one inflammatory clock, our study shows that GrimAge is the biological ageing clock that best associates with different measures of functional capacity, from young to older adulthood.
Authors
- Sophie Guyonnet (ORCID: https://orcid.org/0000-0001-9527-5282)
- Matías Fuentealba (ORCID: https://orcid.org/0000-0001-7353-4394)
- Fabien Pillard (ORCID: https://orcid.org/0000-0003-3381-9744)
- Juan Luis Sánchez‐Sánchez (ORCID: https://orcid.org/0000-0002-2507-6015)
- Paul Bensadoun (ORCID: https://orcid.org/0000-0001-5966-3560)
- Jean-Marc Lemaı̂tre (ORCID: https://orcid.org/0000-0002-6492-5219)
- Philipe de Souto Barreto (ORCID: https://orcid.org/0000-0002-8860-425X)
- David Furman (ORCID: https://orcid.org/0000-0002-3654-9519)
- Yves Rolland (ORCID: https://orcid.org/0000-0002-1157-0215)
- Bruno Vellas
Institutions
- Centre National de la Recherche Scientifique (FR)
- Buck Institute for Research on Aging (US)
- Université Toulouse III - Paul Sabatier (FR)
- Inserm (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Université de Montpellier (FR)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Centre de Recherches en Cancérologie de Toulouse (FR)
- Institute for Regenerative Medicine & Biotherapy (FR)
- Clinique du Sport (FR)
- Stanford Medicine (US)
- Hôpital Saint Eloi (FR)
- Stanford University (US)
Publication Details
- Journal
- Journal of Cachexia Sarcopenia and Muscle
- Published
- 2025-08-01
- DOI
- https://doi.org/10.1002/jcsm.70046
- Citations
- 1
- Primary Topic
- Health, Environment, Cognitive Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.20
Funders
- Pfizer
- Les Laboratories Pierre Fabre
- Région Occitanie Pyrénées-Méditerranée
- Descartes Centre voor Wetenschapsgeschiedenis en Wetenschapsfilosofie, Universiteit Utrecht
- European Regional Development Fund