Morphological changes in CA3 pyramidal neurons after transient global ischemia
Surviving CA3 pyramidal neurons exhibit greater adaptability to ischemic stress compared with vulnerable CA1 neurons, possibly explaining their differential survival. Pharmacological stabilization of neuronal morphology may offer a promising therapeutic strategy for ischemic stroke.
Authors
- Peilin Zhen (ORCID: https://orcid.org/0000-0003-3834-8603)
- Zhongshan Shi (ORCID: https://orcid.org/0000-0002-5802-7332)
- Zhi Guo (ORCID: https://orcid.org/0000-0001-5796-1185)
- Meijuan Zhou (ORCID: https://orcid.org/0000-0003-4962-3164)
- Xia Hu (ORCID: https://orcid.org/0000-0002-6413-5807)
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen Memorial Hospital (CN)
- Jiangmen Central Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Neuroreport
- Published
- 2025-08-08
- DOI
- https://doi.org/10.1097/wnr.0000000000002206
- Primary Topic
- Neuroscience and Neuropharmacology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00