Long-Term Observations of the First Human Implantation of an Artificial Endothelial Layer for Endothelial Dysfunction: A Pilot Study
This small pilot series of the first human EndoArt implantation observed a significant reduction of corneal edema over time and a favorable safety profile in select patients. Although these findings are encouraging, they should be interpreted with caution given the limited sample size. Larger, controlled studies are needed to better understand the safety, efficacy, and long-term outcomes of this synthetic implant.
Authors
- Emanuel Reitemeyer (ORCID: https://orcid.org/0000-0002-8855-3958)
- Charles G. Eberhart (ORCID: https://orcid.org/0000-0002-2910-9427)
- Hyeck-Soo Son (ORCID: https://orcid.org/0000-0003-1065-4035)
- Maximilian Friedrich (ORCID: https://orcid.org/0009-0000-8699-4613)
- Gerd Uwe Auffarth (ORCID: https://orcid.org/0000-0002-6927-5251)
- Victor Aristide Augustin (ORCID: https://orcid.org/0000-0002-6315-8484)
- Louise Blöck
- Oliver Hassel
- N. C. Henningsen (ORCID: https://orcid.org/0000-0003-4218-0997)
Institutions
- Johns Hopkins University (US)
- Heidelberg University (DE)
Publication Details
- Journal
- Cornea
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1097/ico.0000000000003972
- Citations
- 1
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.36