Injectable-Only Overlapping Buprenorphine Starting Protocol in a Low-Threshold Setting

This retrospective cohort study found that a novel injectable-only overlapping buprenorphine starting protocol had a relatively high rate of completion and 2-month retention in a low-threshold setting for individuals with OUD who used fentanyl, most of whom were experiencing homelessness. These findings suggest that this protocol is a promising potential pathway for patients to start buprenorphine in the outpatient setting.

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Publication Details

Journal
JAMA Network Open
Published
2025-08-15
DOI
https://doi.org/10.1001/jamanetworkopen.2025.27016
Citations
7
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
13.15

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article

Injectable-Only Overlapping Buprenorphine Starting Protocol in a Low-Threshold Setting

Callan Fockele, Timothy A. Johnson, Richard C. Waters, Jared W. Klein et al.
7 citations
JAMA Network Open
Opioid Use Disorder Treatment
13.15
article

Injectable-Only Overlapping Buprenorphine Starting Protocol in a Low-Threshold Setting

Callan Fockele, Timothy A. Johnson, Richard C. Waters, Jared W. Klein, Charlotte Bell, A Gérard, L Hurtado, Jeremy Hoog, Penelope Toland, Joseph Valley, Mary Ann Kallsen
article en
7 citations

Abstract

This retrospective cohort study found that a novel injectable-only overlapping buprenorphine starting protocol had a relatively high rate of completion and 2-month retention in a low-threshold setting for individuals with OUD who used fentanyl, most of whom were experiencing homelessness. These findings suggest that this protocol is a promising potential pathway for patients to start buprenorphine in the outpatient setting.

JAMA Network OpenVol. 8(8)
University of Washington (US), Downtown Women's Health Care (US)
Washington State University
Reduced inequalities
Openalex Percentile: Top 1%
Opioid Use Disorder Treatment
13.15
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