Successful management of a case of eclampsia complicated by HELLP syndrome and its sequelae

When severe preeclampsia progresses to its most severe stage, eclampsia and HELLP syndrome (Hemolysis, Elevated Liver Enzymes, and Low Platelet syndrome, HELLP syndrome) can occur. The incidence rates of eclampsia and HELLP syndrome are extremely low, and the condition complicated by the rupture of a subcapsular hepatic hematoma is even rarer, which seriously endangers the patient’s life.This article reports a case where a patient gave birth spontaneously outside the hospital, suddenly developed eclampsia, and was complicated by Hellp syndrome and the rupture of a subcapsular hepatic hematoma. During the operation, extensive peeling of the capsule on the diaphragmatic surface of the right lobe of the liver was observed, and the blood loss was approximately 8000 ml. Postoperatively, the important indicators deteriorated rapidly by hundreds of times, leading to hepatorenal failure, a small amount of subarachnoid hemorrhage in the right parietal lobe, a large amount of pleural effusion accompanied by atelectasis. After multiple multidisciplinary case discussions both within and outside the province, the patient was finally cured and discharged from the hospital.Through in-depth analysis of this highly challenging case, this article systematically summarizes its pathogenesis, clinical features, and treatment experience, aiming to provide valuable reference for clinicians and improve their understanding, diagnosis, and treatment levels of such diseases.

Authors

Institutions

Publication Details

Journal
BMC Pregnancy and Childbirth
Published
2025-08-14
DOI
https://doi.org/10.1186/s12884-025-08008-x
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Successful management of a case of eclampsia complicated by HELLP syndrome and its sequelae

Hua Zhang, Han Sucan, Zhu Liangxi
BMC Pregnancy and Childbirth
Pregnancy and preeclampsia studies
article

Successful management of a case of eclampsia complicated by HELLP syndrome and its sequelae

Hua Zhang, Han Sucan, Zhu Liangxi
article en

Abstract

When severe preeclampsia progresses to its most severe stage, eclampsia and HELLP syndrome (Hemolysis, Elevated Liver Enzymes, and Low Platelet syndrome, HELLP syndrome) can occur. The incidence rates of eclampsia and HELLP syndrome are extremely low, and the condition complicated by the rupture of a subcapsular hepatic hematoma is even rarer, which seriously endangers the patient’s life.This article reports a case where a patient gave birth spontaneously outside the hospital, suddenly developed eclampsia, and was complicated by Hellp syndrome and the rupture of a subcapsular hepatic hematoma. During the operation, extensive peeling of the capsule on the diaphragmatic surface of the right lobe of the liver was observed, and the blood loss was approximately 8000 ml. Postoperatively, the important indicators deteriorated rapidly by hundreds of times, leading to hepatorenal failure, a small amount of subarachnoid hemorrhage in the right parietal lobe, a large amount of pleural effusion accompanied by atelectasis. After multiple multidisciplinary case discussions both within and outside the province, the patient was finally cured and discharged from the hospital.Through in-depth analysis of this highly challenging case, this article systematically summarizes its pathogenesis, clinical features, and treatment experience, aiming to provide valuable reference for clinicians and improve their understanding, diagnosis, and treatment levels of such diseases.

BMC Pregnancy and ChildbirthVol. 25(1)
Affiliated Hospital of Jining Medical University (CN)
Good health and well-being
Openalex Percentile: Top 74%
Pregnancy and preeclampsia studies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Successful management of a case of eclampsia complicated by HELLP syndrome and its sequelae — Hua Zhang, Han Sucan, et al. · BMC Pregnancy and Childbirth (2025) | TGRS Research Map | TGRS