Obesity- and Lipid-Related Traits May Causally Contribute to Sepsis-Associated Acute Kidney Injury
For Septic-AKI, GWAS identified a novel genetic susceptibility locus ( GALNTL6 ), which is also associated with cardiometabolic traits. We then further found that obesity- and lipid-related traits are possible contributors to the pathogenesis of Septic-AKI.
Authors
- Tadanaga Shimada (ORCID: https://orcid.org/0000-0002-0505-5145)
- Keith R. Walley (ORCID: https://orcid.org/0000-0003-4232-7266)
- Nozomi Takahashi (ORCID: https://orcid.org/0000-0001-9417-2396)
- Kyle R. Campbell (ORCID: https://orcid.org/0000-0003-2980-3280)
- Taka‐aki Nakada (ORCID: https://orcid.org/0000-0002-4480-556X)
- James A. Russell (ORCID: https://orcid.org/0000-0003-1484-7539)
Institutions
- University of British Columbia (CA)
- St. Paul's Hospital (CA)
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2025-08-14
- DOI
- https://doi.org/10.1097/ccm.0000000000006812
- Citations
- 1
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.43