Rhabdomyolysis and Hepatitis Associated with Oropouche Fever: Brazil

This study presents a rare case of rhabdomyolysis caused by Orthobunyavirus oropoucheense in a 21-year-old male patient in the Amazon region. The diagnosis was confirmed by the reverse transcription polymerase chain reaction test. Neutropenia, thrombocytopenia, and hepatitis were also identified by laboratory tests, demonstrating the clinical relevance as they are alterations with potential severity. The patient's good recovery is noteworthy, with only simple analgesia and intravenous hydration. The case highlights the need for better clarification regarding the pathophysiology of this distinct arbovirus.

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Publication Details

Journal
American Journal of Tropical Medicine and Hygiene
Published
2025-08-14
DOI
https://doi.org/10.4269/ajtmh.25-0107
Primary Topic
Vector-borne infectious diseases
Type
article
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article

Rhabdomyolysis and Hepatitis Associated with Oropouche Fever: Brazil

L. Santos, Karen Spadari Ferreira, Guilherme Rafael Gomide Pinheiro, João Hugo Abdalla Santos et al.
American Journal of Tropical Medicine and Hygiene
Vector-borne infectious diseases
article

Rhabdomyolysis and Hepatitis Associated with Oropouche Fever: Brazil

L. Santos, Karen Spadari Ferreira, Guilherme Rafael Gomide Pinheiro, João Hugo Abdalla Santos, Lídia Freire Abdalla
article en

Abstract

This study presents a rare case of rhabdomyolysis caused by Orthobunyavirus oropoucheense in a 21-year-old male patient in the Amazon region. The diagnosis was confirmed by the reverse transcription polymerase chain reaction test. Neutropenia, thrombocytopenia, and hepatitis were also identified by laboratory tests, demonstrating the clinical relevance as they are alterations with potential severity. The patient's good recovery is noteworthy, with only simple analgesia and intravenous hydration. The case highlights the need for better clarification regarding the pathophysiology of this distinct arbovirus.

American Journal of Tropical Medicine and HygieneVol. 113(5)
Universidade do Estado do Amazonas (BR), Hospital Adventista Silvestre (BR)
Openalex Percentile: Top 79%
Vector-borne infectious diseases
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Rhabdomyolysis and Hepatitis Associated with Oropouche Fever: Brazil — L. Santos, Karen Spadari Ferreira, et al. · American Journal of Tropical Medicine and Hygiene (2025) | TGRS Research Map | TGRS